Synthetic Route of 10075-63-5,Some common heterocyclic compound, 10075-63-5, name is 1,5-Dimethoxynaphthalene, molecular formula is C12H12O2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Under nitrogen, 300 mg (1.1 mmol) of 1,3,4-tri-O-acetyl-2,6-dideoxy-L-rhamnose and 620 mg (3.3 mmol) of 1,5-dimethoxynaphthalene After mixing with 30 mL of 1,2-dichloroethane, 27.94 mg (0.11 mmol) of I2 and 5.27 muL (0.033 mmol) of Et3SiH catalyst were added at a temperature of 25 C, and the TLC plate (PE: EA = 6: 1) to monitor the reaction, the reaction solution was isolated and purified to obtain 40.2 mg of the product as 3,4-di-O-acetyl-2,6-dideoxy-L-squirrel Sugar 1,5-dimethoxynaphthalene-beta-C-glycoside in a yield of 91%.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1,5-Dimethoxynaphthalene, its application will become more common.