Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 126940-10-1, name is 1-Fluoro-3-(methoxymethoxy)benzene, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C8H9FO2
A solution of 270 ML (430 MMol) n-butyllithium (1.6 M in hexanes) in 800 ML tetrahydrofuran was cooled to -78C. To this solution was added a solution of 60 gm (384 MMol) 1-(methoxymethoxy)-3-fluorobenzene in 100 ML tetrahydrofuran over 30 minutes.. The resulting mixture was stirred for 1 hour and was then rapidly quenched with 67.5 gm (423 MMol) bromine.. The reaction mixture was stirred for 30 minutes and was then partitioned by the addition of 500 ML methyltert-butyl ether and 300 ML saturated aqueous sodium thiosulfate.. The organic phase was dried over sodium sulfate and concentrated under reduced pressure.. The residual oil was distilled (kugelrorh, 70-100C, 0.1 torr) to provide 81.7 gm (91%) of the desired compound as a colorless oil.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 126940-10-1.
Reference:
Patent; ELI LILLY AND COMPANY; EP1204660; (2004); B1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem