Application of 92028-21-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 92028-21-2 name is 6-Methoxy-[1,1′-biphenyl]-3-amine hydrochloride, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Example 6 N-(4-Methoxy-3-phenyl)phenyl-(2-chloro-5-nitrophenyl)carboxamide The title compound (0.586 g) was obtained as a crystalline solid according to the procedure described in Example 2 using (4-methoxy-3-phenyl)aniline hydrochloride (0.478 g), pyridine (5 ml) and 2-chloro-5-nitrobenzoyl chloride (0.535 g). 1H-NMR (400 MHz, CDCl3, TMS): delta(ppm) 3.95 (3H, s), 7.31-7.46 (4H, m), 7.63-7.69 (3H, m), 8.27 (1H, dd, J=8.8, 2.7 Hz), 8.67 (1H, d, J=2.7 Hz), 8.54 (1H, d, 2.2 Hz).
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 6-Methoxy-[1,1′-biphenyl]-3-amine hydrochloride, and friends who are interested can also refer to it.
Reference:
Patent; SANKYO COMPANY, LIMITED; US2003/134859; (2003); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem