Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 33839-11-1, name is 4-Bromo-2-ethyl-1-methoxybenzene, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 4-Bromo-2-ethyl-1-methoxybenzene
A mixture of bromide (1.3g, 6. 02MMOL, from step 1), 1-CYCLOPENTYL-2-PROPEN-1-OL (1.14g, 9. 07mmot), DICHLOROBIS (TRIPHENYLPHOSPHINE) PALLADIUM (LL) (85 mg, 0 12 mmol), sodium bicarbonate (0.61 g, 7.25 MMOT) in N-METHYLPYRROLIDINONE (12mL) was heated to 140 C under N2 for 5h. The reaction mixture was partitioned between 1N HCl and EtOAc. The organic layer was washed with saturated NaHCO3, brine, dried over Na2SO4 and concentrated’to a brown oil. The oil was purifed by silica gel chromatography to give the title compound as a yellow oil (0.74g, 47%). 1H NMR (CDCL3): No. ?1. 17 (t, 3H, J = 7.6 Hz), 1. 54-1. 80 (M, 9H), 1.17 (q, 2H, J= 7. 6 HZJ,-2. 73 (m, 2H), 2.84 (m, 2H), 3.80 (s, 3H), 6.75 (d, 1H, J= 8. 0Hz), 6.97 (m, 2H).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 33839-11-1.
Reference:
Patent; PFIZER INC.; WO2004/74270; (2004); A2;,
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