Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 20059-73-8, name is 2-(4-(Aminomethyl)phenoxy)-N,N-dimethylethanamine, A new synthetic method of this compound is introduced below., SDS of cas: 20059-73-8
Table HH: Examples of amides prepared from 3-(2-chlorophenyl)isoxazoIe-5-carboxyIic acid; A 20 mL scintillation vial is charged with a solution of 3-(2-chlorophenyl)isoxazole-5- carboxylic acid in DMF (1.0 eq, 6.96 mmol, 35.31 mg), a solution of HATU in DMF (1.20 eq, 8.84 mmol), a solution of pre-weighed 0.6 mmol amine monomer in DMF(1.30 eq, 3.0 mL DMF), and a solution of N, N-diisopropylamine in DMF (2.0 eq, 14.74 mmol). The vial was capped and placed in a heater/shaker at 90 0C overnight. The mixture is then passed through a solid phase extraction column with silica carbonate medium using MeOH. The solvent was removed and the crude material was purified by HPLC method (n) and the solvents evaporated.
The synthetic route of 20059-73-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; ABBOTT LABORATORIES; WO2009/11850; (2009); A2;,
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