Brief introduction of C8H8F3NO

The synthetic route of 93919-56-3 has been constantly updated, and we look forward to future research findings.

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 93919-56-3, name is (4-(Trifluoromethoxy)phenyl)methanamine, A new synthetic method of this compound is introduced below., Application In Synthesis of (4-(Trifluoromethoxy)phenyl)methanamine

Step 2 Nitro-4-(4-trifluoromethoxy-benzylamino)-benzoic acid allyl ester; 5.0 g of 4-fluoro-3-nitro-benzoic acid allyl ester (22 mmol) were dissolved in 100 ml ethanol. 4.25 g of 4-(trifluoromethoxy)-benzylamine (22 mmol) were added and stirred at room temperature for 1 h. The product was extracted from methylenchloride/water and dried over sodium sulfate. The crude product was crystallized from isopropyl ether to result in yellow crystals (7.5 g). MS(ISP): 397.2 (M+H)+.

The synthetic route of 93919-56-3 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Bleicher, Konrad; Heinrich Nettekoven, Matthias; Pflieger, Philippe; Roever, Stephan; US2006/89367; (2006); A1;,
Ether – Wikipedia,
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