Application of 4342-46-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 4342-46-5, name is 4-Methoxycyclohexanamine belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Ethylcyclohexane (1200 mL) was added to the autoclave, stirring was started, and 220 g (2 mol) of formamide was added to the solution at a concentration of 40%. After stirring for 10 minutes, 1-amino-4-methoxycyclohexane (130 g, 1 mol) was added. ,Into the reaction kettle to pass CO, so that the pressure in the kettle reaches 0.2MPa, heated to 130 C, heat 20h, in the control of raw materials <2%, the reaction is over, cooled to 25 ~ 30 C, dilute hydrochloric acid was added dropwise to the reaction solution , Adjust the pH to 5-6, there is a solid precipitation, filter out the product, filter cake shampoo once,cis-8-Methoxy-1,3-diazaspiro[4,5]-nonane-2,4-dione, 184 g, yield 92%.
The synthetic route of 4-Methoxycyclohexanamine has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Henan Zi Wei Xing Chemical Co., Ltd.; Wu Doucan; Mao Longfei; Li Wei; Lu Zhiguo; Wang Zhenggang; Lu Biao; Jia Shuhong; Yuan Zhiguo; (10 pag.)CN107827881; (2018); A;,
Ether – Wikipedia,
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