Application of 7025-06-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 7025-06-1, name is 1-Bromo-2-phenoxybenzene belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Dissolve 27.4 g (110 mmol) of 1-bromo-2-diphenyl ether in 350 ml of dry tetrahydrofuran,Cool the reaction system to -78 °C50 ml of n-butyllithium in 2.5 M (110 mmol) hexane was slowly added dropwise,Then keep the system stirred at -70°C for 1 hour.Then 33.8 g (100 mmol) of 4,5-dibromo-9H-fluorenone was dissolved in 85 ml of tetrahydrofuran and added dropwise at -70°C.The system was slowly warmed to room temperature, quenched with ammonium chloride and subsequently evaporated in a rotary evaporator, and the organic solution was collected, and the resulting intermediate (A) was dissolved in the organic solution.
The synthetic route of 1-Bromo-2-phenoxybenzene has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Changchun Hai Purunsi Technology Co., Ltd.; Zhou Wenting; Cai Hui; (29 pag.)CN107880053; (2018); A;,
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