Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 701-07-5, name is 2-(2′-Bromophenoxy)propane, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 701-07-5
General procedure: A degassed solution containing the aryl bromide (9a, 183 mg, 0.852 mmol), anhydrous LiCl (286 mg, 6.82 mmol), Ph3P (112 mg, 0.426 mmol) and Pd(Ph3P)2Cl2 (71.7 mg,0.102 mmol) in anhydrous diglyme (2 mL, final concentration of 9a ca. 0.15 M) was treated dropwise with allyltri(n-butyl)tin (0.32 mL, 1.02 mmol). The reaction mixture was heated at 130C under an argon atmosphere. A sample taken at 6 h and worked up allowed the isolation of 1-allyl-2-isopropoxybenzene.3IR (film): 605, 734, 864, 995, 1046, 1174, 1287, 1372, 1383, 1489, 1587, 1638, 2931,2978, 3077 cm-1. 1H NMR (300 MHz, CDCl3): d 1.33 (d, J D 6.0 Hz, 6H), 3.37 (d, J D6.7 Hz, 2H), 4.54 (septet, J D 6.0 Hz, 1H), 5.00-5.09 (m, 2H), 5.93-6.03 (m, 1H), 6.83-6.89 (m, 2H), 7.12-7.18 (m, 2H). 13C NMR (75 MHz, CDCl3): d 22.2, 34.6, 69.9, 113.0,115.2, 120.2, 127.1, 129.7, 129.9, 137.2, 155.5. MS (EI, 70 eV): m/z (%) 91 (13), 115(12), 119 (46), 133 (46), 134 (100), 135 (10), 176 [M]C(66), 177 [MC1]C(9). MS found:176.1207; C12H16O requires m/z: 176.1201. When the reaction was heated during 14 h, complete consumption of the starting material took place, as determined by GC analysis. Then, the reaction mixture was allowed to attain ambient temperature and was diluted with 25 mL of hexanes and filtered through a short pad of Florisil and Celite (1:1). The filtrate was washed successively with saturated NaF (4 £ 10 mL), H2O (3 £ 10 mL), brine (15 mL) and H2O2 (10 mL of a0.12% P/V solution), dried over Na2SO4 and evaporated in vacuo. The oily residue was re-dissolved in CH2Cl2 and stirred an additional period of 12 h with 200 mg activated fluorous silica. Filtration and evaporation of volatiles afforded 90 mg (73%) of the expected beta-methylstyrene (3), as a colorless oil.IR (film): 606, 782, 862, 959, 1049, 1176, 1289, 1383, 1484, 1596, 1655, 2876, 2933,3070 cm-1. 1H NMR (300 MHz, CDCl3): d 1.35 (d, J D 5.9, 6H, Me2-CH), 1.90 (dd, J D1.5 and 6.6, 3H, Me-CH=CH-Ar), 4.57 (septet, J D 5.9, 1H, Me2-CH), 6.22 (dq, J D 6.0,13.9 and 15.2, 1H, Me-CH=CH-Ar), 6.72 (dq, J D 1.5 and 15.9, 1H, CH3-CH=CH-Ar),6.85-6.90 (m, 2H, ArH), 7.14 (dt, J D 1.5 and 7.7, 1H, 4-H), 7.41 (dd, J D 1.4 and 7.5,1H, 6-H). 13C NMR (75 MHz, CDCl3): d 18.9 (Me-CH=CH-Ar), 22.2 (Me2-CH-O), 70.8(Me2-CH), 114.3 (6-C), 120.7 (5-C), 125.8 (2-C), 125.9 (CH3-CH=CH-Ar), 126.4 (CH3-CH=CH-Ar), 127.5 (3-C), 128.2 (5-C), 154.6 (1-C). MS (EI, 70 eV): m/z (%) 77 (10), 91(24), 105 (13), 107 (9), 115 (17), 117 (12), 119 (69), 133 (54), 134 (100), 147 (12), 176[M]C(52), 177 [MC1]C(7). MS found m/z D 176.1198; C12H16O (MC) requires m/z D176.1201. The spectral data were in full agreement with those described.2,3,5,8
According to the analysis of related databases, 701-07-5, the application of this compound in the production field has become more and more popular.
Reference:
Article; Simonetti, Sebastian O.; Larghi, Enrique L.; Kaufman, Teodoro S.; Organic Preparations and Procedures International; vol. 47; 3; (2015); p. 227 – 231;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem