Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 70627-52-0, name is N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline, This compound has unique chemical properties. The synthetic route is as follows., Formula: C20H16FNO
To a solution of [RhCl(cod)]2(2 mol %) and N-(4-(benzyloxy)benzylidene)-4-fluoroaniline(1B, 0.5 mmol) in THF (1.25 mL) at room temperature was added BF3·Et2O (0.6 mmol), andthen it stirred for 30 min at the same temperature. Subsequently, 5,6-dihydro-2H-pyran-2-one (2h, 0.6 mmol) was added to the suspension mixture, and then 1.0 M Et2Zn in hexane (1.5 mmol, 1.5 mL) was gradually added to the mixture and stirred for 24 h. The mixture was quenched with sat. NH4Cl and extracted with AcOEt. The AcOEt layer was washed with sat. NaCl and dried over MgSO4. The solvent was removed in vacuo, and the residue was purified by column chromatography (AcOEt/hexane = 4:6) and anti diastereomer was obtained in 46% (93.3 mg) [2].
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 70627-52-0.
Reference:
Article; Isoda, Motoyuki; Sato, Kazuyuki; Kunugi, Yurika; Tokonishi, Satsuki; Tarui, Atsushi; Omote, Masaaki; Minami, Hideki; Ando, Akira; Beilstein Journal of Organic Chemistry; vol. 12; (2016); p. 1608 – 1615;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem