Related Products of 123652-95-9, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 123652-95-9, name is (3-Fluoro-4-methoxyphenyl)methanamine belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
[00330] To a solution of compound 2, 19 and Et3N in DMF at rt. then HATU was added at rt.After stirring for lh at rt, the reaction was diluted with water and extracted with EA, washed byK2C03 and brine, dried over Na2SO4 and concentrated and purified by FCC to afford compound20. ?H NMR (400 MHz, CDC13): 3 8.46 (s, 1H), 8.42 (s, 1H), 7.10-7.06 (m, 2H), 6.94-6.90 (m,1H), 6.47-6.44 (m, 1H), 4.57 (d, J = 6.0 Hz, 2H), 3.87 (s, 3H); mlz (ESI+) (M+H)+ = 313.05.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, (3-Fluoro-4-methoxyphenyl)methanamine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY; YANG, Wenjin; CHEN, Che-Hong; MOCHLY-ROSEN, Daria; WO2014/160185; (2014); A2;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem