Adding a certain compound to certain chemical reactions, such as: 207226-31-1, name is 1,3-Dibromo-5-(trifluoromethoxy)benzene, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 207226-31-1, SDS of cas: 207226-31-1
Dibromide D-l-2a (3.0 g, 9.38 mmol), sodium-tert-butoxide (1.26 mg, 13.13 mmol), BINAP (584 mg, 0.938 mmol) and tris-(dibenzylideneacetone)-palladium (85.9 mg, 0.094 mmol) are suspended in 60 mL toluene, combined with benzophenonimine (2.04 g, 11.25 mmol), and refluxed under an argon atmosphere for 3 d. Then the reaction mixture is filtered and the solvent is eliminated by distillation.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1,3-Dibromo-5-(trifluoromethoxy)benzene, and friends who are interested can also refer to it.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; WO2009/3999; (2009); A2;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem