Adding a certain compound to certain chemical reactions, such as: 494-99-5, name is 1,2-Dimethoxy-4-methylbenzene, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 494-99-5, Recommanded Product: 1,2-Dimethoxy-4-methylbenzene
General procedure: A mixture of 3,4-disubstituetedtoluene (1 mmol), NBS(213 mg, 1.2 mmol) and AIBN(16 mg, 0.1 mmol) in anhydrous CCl4 (15 mL) was refluxed and monitored by TLC. After refluxing for 4 h, the reaction mixturewas filtered. The filtrate was concentrated to crude product, which was used inthe subsequent reaction without further purification
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,2-Dimethoxy-4-methylbenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Ge, Bing-Chen; Feng, Hong-Fang; Cheng, Yu-Fang; Wang, Hai-Tao; Xi, Bao-Ming; Yang, Xue-Mei; Xu, Jiang-Ping; Zhou, Zhong-Zhen; European Journal of Medicinal Chemistry; vol. 141; (2017); p. 440 – 445;,
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