Analyzing the synthesis route of 4-Bromo-3-methoxyaniline

According to the analysis of related databases, 19056-40-7, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 19056-40-7, name is 4-Bromo-3-methoxyaniline, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 19056-40-7

Intermediate 235; Diethyl IFf 4-bromo-3-methoxyphenyl)amino1methylenelmalonate; To a solution of 4-bromo-3-methoxyaniline (25 g, 0.12 mol) in CH3CN (150 mL) was added diethylethoxymethylene malonate (27 mL, 0.13 mol). After 20 hours, the solvent was removed under reduced pressure and the residue dissolved in EtOAc. Hexane was added, and the resulting precipitate collected to give 37 g (80percent) off-white solid. 1H NMR: 10.68 (d, 1 H), 8.38 (d, 1 H), 7.52 (d, 1 H), 7.20 (d, 1 H), 6.91 (dd, 1 H), 4.20 (q, 2 H), 4.11 (q, 2 H), 3.86 (s, 3 H), 1.23 (m, 6 H); m/z: 372.

According to the analysis of related databases, 19056-40-7, the application of this compound in the production field has become more and more popular.

Reference:
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2007/119046; (2007); A1;,
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