In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 39021-83-5, name is 1,4-Dimethoxy-2,3-dimethylbenzene belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. COA of Formula: C10H14O2
5.2. Formylation of Dimethoxybenzenes by Means of the Duff Reaction1 equivalent of dimethoxybenzene was dissolved in 20 ml of TFA and 1.05 equivalents or urotropin were added to the resulting solution. The reaction mixture was brought to reflux for 2 hours under anhydrous conditions. The TFA was evaporated off under reduced pressure, the residue was dissolved in 100 ml of ether and the organic solution was washed with water (3 times 50 ml) and then dried over MgSO4. The solvent was evaporated off and the residue was subjected to column chromatography, elution being carried out with an 80:20 mixture of light mineral spirit (60-80 C.):diethyl ether.5.2.1. 2,5-Dimethoxy-3,4-dimethylbenzaldehydeThe process was carried out as described in point 5.2 above, using 2.270 g (0.01366 mol) of 1,4-dimethoxy-2,3-dimethylbenzene. The title product was isolated in the form of a white solid (1.18 g, 44%).
The synthetic route of 39021-83-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; bioMerieux; US7626018; (2009); B2;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem