Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 658-89-9, name is 4-(Trifluoromethoxy)benzene-1,2-diamine, This compound has unique chemical properties. The synthetic route is as follows., Formula: C7H7F3N2O
N1-pyrrolidine cyanoguanidine (72 mg, 0.52 mmol) and 4-trifluoro methoxy phenylene diamine (0.1 g, 0.52 mmol) were dissolved in distilled water (10 ml) at room temperature, and then hydrochloric acid(0.1 ml, 1.04 mmol) was added thereto, and stirred with reflux at 110 C. for 2 hr. The reaction mixture was added by 10% potassium hydroxide solution, and then the obtained solid was filtrated under reduced pressure, and was washed with distilled water. The filtrated solid was dried under reduced pressure. The title compound was produced in brown solid phase(20 mg, 12.2%). 1H NMR (600 MHz, CD3OD) delta 7.22 (d, J=8.4 Hz, 1H), 7.13 (s, 1H), 6.90 (d, J=8.4 Hz, 1H), 3.49 (br s, 4H), 1.92 (s, 4H); LC-MS m/z 235.1 [M+1]
According to the analysis of related databases, 658-89-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; HANALL BIOPHARMA CO., LTD.; KIM, Hong Woo; LEE, Ji Sun; HEO, Hye Jin; LEE, Hong Bum; JEONG, Jae Kap; PARK, Ji Hyun; KIM, Seo-il; LEE, Young Woo; US2015/126518; (2015); A1;,
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