Electric Literature of 592-55-2, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 592-55-2 as follows.
Add 3 g of potassium hydroxide solid to a 250 mL flask, then add 30 mL of DMF and stir well. After the above system was stirred for 10 minutes, 2 g of compound 2 was added thereto, and then the system was stirred for 30 minutes. Subsequently, 1.38 mL of was added2-bromoethyl ether, the reaction 18 hours at room temperature. After the reaction was completed, the above system was poured into 400 mL of water and extracted with 400 mL of dichloromethane. The organic layer was dried with 4 g of anhydrous magnesium sulfate and the solvent was evaporated to give a white product in a yield of 81%.
According to the analysis of related databases, 592-55-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Shandong University; Yu Xiaoqiang; Tian Minggang; He Xiuquan; Zhang Ruoyao; (11 pag.)CN106632264; (2017); A;,
Ether – Wikipedia,
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