In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 93919-56-3, name is (4-(Trifluoromethoxy)phenyl)methanamine belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. HPLC of Formula: C8H8F3NO
General procedure: 5.3g (0.02 mol) of methyl N-nitro-1,3-dioxoisoindoline-2-carbimidothioate (3) was dissolved in 120 mL of acetonitrile, and cooled to 0-5, dropped in a quantity of 0.02 mmol of (aryl)methanamine over 5 mins. The reaction was stirred at 0-5 for one hour again. The mixture was filtered, concentrated in vacuo and recrystallised in EtOAc – petroleum ether (1:1) to give pure products 4a~4f.
The synthetic route of 93919-56-3 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Wu, Qinglai; Zhao, Fenghai; Zhu, Xiang; Zhou, Ziyuan; Yang, Dongyan; Xu, Zhihong; Li, Junkai; Qin, Zhaohai; Natural Product Research; (2019);,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem