Recommanded Product: Diphenyl oxide. Siddiqui, AA; Partap, S; Khisal, S; Yar, MS; Mishra, R in [Siddiqui, Aness Ahmad; Partap, Sangh; Khisal, Subuhi; Yar, Mohammad Shahar] Jamia Hamdard, Sch Pharmaceut Educ & Res, Dept Pharmaceut Chem, New Delhi, India; [Mishra, Ravinesh] Baddi Univ Emerging Sci & Technol, Sch Pharm & Emerging Sci, Baddi Solan 173205, Himachal Prades, India published Synthesis, anti-convulsant activity and molecular docking study of novel thiazole pyridazinone hybrid analogues in 2020.0, Cited 34.0. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8.
Pyridazinone analogues have been known to be potential candidates for anticonvulsant agents. We have identified several pyridazinone-based anticonvulsant agents. As a continuation to our previous research, a series of hybrid pyridazinone-thiazole connected through amide linkage were designed and synthesized. Among these, compound SP-5F demonstrated significant anticonvulsant activity with median effective dose of 24.38 mg/kg (MES) and 88.23 mg/kg (scPTz). Results of GABA estimation showed a marked increase in the GABA level when compared with control. Molecular docking studies at the active site of GABA receptor, further confirmed the GABA modulatory effects of SP-5F.
Recommanded Product: Diphenyl oxide. Bye, fridends, I hope you can learn more about C12H10O, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Ether – Wikipedia,
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