Weirich, Luisa’s team published research in Physical Chemistry Chemical Physics in 2021 | CAS: 33100-27-5

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Name: 1,4,7,10,13-Pentaoxacyclopentadecane

Weirich, Luisa; Merten, Christian published their research in Physical Chemistry Chemical Physics in 2021. The article was titled 《Induced VCD and conformational chirality in host-guest complexes of a chiral ammonium salt with crown ethers》.Name: 1,4,7,10,13-Pentaoxacyclopentadecane The article contains the following contents:

The hydrogen bonded complexes of the chiral ammonium salt α-methylbenzyl ammonium chloride (MBA-H+Cl-) and the achiral crown ethers 18c6 and 15c5 serve as model systems to investigate the effect of host-guest complex formation on the conformational preferences of the macrocycles. We demonstrate that the intermol. interactions result in new VCD signatures, that can be assigned to vibrational modes of the crown ethers. Based on a detailed conformational anal., we investigate the origin of these signatures and discuss induced VCD (iVCD) and conformational chirality as possible sources of VCD intensity. The macrocycle in the MBA-H+/18c6 complex prefers either an achiral D3d-sym. conformation, which gives rise to iVCD, or chiral conformations, that feature individual contributions to the VCD spectrum. For the MBA-H+/15c5 complex, the contributions of the macrocycle to the VCD signatures are less pronounced and found to arise solely from conformational chirality. Therefore, anal. of the VCD signatures confirms that the small chiral guest mol. is able to affect the conformational preferences of a macrocyclic host. The study thus demonstrates the suitability of VCD spectroscopy for the characterization of analogous supramol. host-guest complexes. The results came from multiple reactions, including the reaction of 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Name: 1,4,7,10,13-Pentaoxacyclopentadecane)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Name: 1,4,7,10,13-Pentaoxacyclopentadecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem