Feng, Siliang; Li, Senhao; Kang, Xiaoyu; Liu, Keliang published an article in Journal of Chemical Research. The title of the article was 《One step synthesis of biotinylated amino acids》.COA of Formula: C24H22N2O4 The author mentioned the following in the article:
A rapid method is reported for the preparation of biotinylated 4-amino-D-phenylalanine(D-Aph) with Fmoc (Fmoc = 9-fluorenylmethoxycarbonyl) as the protecting group at the α-amino. Different coupling reagents and conditions were studied to get the biotinylated compound Coupling reagents like 1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate and BOP were found to be very efficient. Biotinylated Boc-L-Aph and biotinylated Fmoc-L-lysine were also successfully prepared by this method. In the part of experimental materials, we found many familiar compounds, such as Fmoc-D-Phe(4-NH2)-OH(cas: 324017-21-2COA of Formula: C24H22N2O4)
Fmoc-D-Phe(4-NH2)-OH(cas: 324017-21-2) belongs to ethers.Ethers do have nonbonding electron pairs on their oxygen atoms, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. COA of Formula: C24H22N2O4 The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem