Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 73724-45-5, formula is C18H17NO5, Name is Fmoc-Ser-OH. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Product Details of C18H17NO5.
Zhou, Zhixuan;Maxeiner, Konrad;Moscariello, Pierpaolo;Xiang, Siyuan;Wu, Yingke;Ren, Yong;Whitfield, Colette J.;Xu, Lujuan;Kaltbeitzel, Anke;Han, Shen;Muecke, David;Qi, Haoyuan;Wagner, Manfred;Kaiser, Ute;Landfester, Katharina;Lieberwirth, Ingo;Ng, David Y. W.;Weil, Tanja research published 《 In Situ Assembly of Platinum(II)-Metallopeptide Nanostructures Disrupts Energy Homeostasis and Cellular Metabolism》, the research content is summarized as follows. Nanostructure-based functions are omnipresent in nature and essential for the diversity of life. Unlike small mols., which are often inhibitors of enzymes or biomimetics with established methods of elucidation, functions of nanoscale structures in cells are complex and can implicate system-level effects such as the regulation of energy and redox homeostasis. Herein, the authors design a Pt(II)-containing tripeptide that assembles into intracellular fibrillar nanostructures upon mol. rearrangement in the presence of endogenous H2O2. The formed nanostructures blocked metabolic functions, including aerobic glycolysis and oxidative phosphorylation, thereby shutting down ATP production As a consequence, ATP-dependent actin formation and glucose metabolite-dependent histone deacetylase activity are downregulated. Assembly-driven nanomaterials offer a rich avenue to achieve broad-spectrum bioactivities that could provide new opportunities in drug discovery.
73724-45-5, Fmoc-Ser-OH, also known as Fmoc-Ser-OH, is a useful research compound. Its molecular formula is C18H17NO5 and its molecular weight is 327.3 g/mol. The purity is usually 95%.
Fmoc-L-Ser-OH is a synthetic peptide that belongs to the group of glycopeptides. It is used as a model for such compounds and has been shown to have antimicrobial activity in vitro against gram-positive bacteria, especially Staphylococcus epidermidis. This compound was synthesized from 3-mercaptopropionic acid and chloride in the presence of hydroxyl groups and epidermal growth factor. The synthetic pathway can be divided into three steps: (1) condensation of 3-mercaptopropionic acid with hydrochloric acid to yield 3-mercaptoacrylic acid; (2) esterification of 3-mercaptoacrylic acid with glycine to form Fmoc-L-Ser; and (3) deprotection of Fmoc protecting group., Product Details of C18H17NO5
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem