Jiang, Yihui; Wang, Chunlan; Ma, Nana; Chen, Jie; Liu, Chuanfei; Wang, Fang; Xu, Jiakun; Cong, Zhiqi published an article in 2020, the title of the article was Regioselective aromatic O-demethylation with an artificial P450BM3 peroxygenase system.Electric Literature of 578-58-5 And the article contains the following content:
Several simple single- and double-mutants of cytochrome P450BM3 enzymes enabled a highly regioselective O-demethylation of aromatic ethers with H2O2 with the assistance of a dual-functional small mol. (DFSM). The DFSM-facilitated P450BM3 peroxygenase system provides an alternative, simple approach for a key step in the bioconversion of lignin compared with reported NADPH-dependent P 450 monooxygenases. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Electric Literature of 578-58-5
The Article related to regioselective aromatic o demethylation engineering cytochrome p450bm3 peroxygenase, Fermentation and Bioindustrial Chemistry: Macromolecules and other aspects.Electric Literature of 578-58-5
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem