Xia, Wen-Jin; Xin, Yangchun; Zhao, Zhi-Wei; Chen, Xin; Wang, Xiang-Xiang; Li, Yi; Wang, Guanlin; Li, Ya-Min published an article in 2020, the title of the article was Oxidative cascade cyclization of 2-cyano-3-arylaniline derived acrylamides with toluenes, ethers, aliphatic alcohols or simple alkanes.Application In Synthesis of 2-Methylanisole And the article contains the following content:
An oxidative radical cascade cyclization of 2-cyano-3-arylaniline-derived acrylamides I (R1 = H, 3-Me, 4-CN, 3,5-Cl2, etc.; R2 = Me, PhCH2; R3 = Me, Ph, PhCH2) with hydrocarbons, e.g., toluene, THF, cyclohexane, etc., is described. The present reaction exhibited a wide substrate scope, and toluenes, ethers, aliphatic alcs. and simple alkanes were employed as coupling partners, providing access to alkyl-substituted pyrido[4,3,2-gh]phenanthridines, e.g., II from toluene. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Application In Synthesis of 2-Methylanisole
The Article related to arylcyanophenyl acrylamide cascade radical oxidative cyclization hydrocarbon, alkyl pyridophenanthridine preparation, Heterocyclic Compounds (More Than One Hetero Atom): Other 6-Membered Rings, Two Hetero Atoms and other aspects.Application In Synthesis of 2-Methylanisole
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