Griffiths, Oliver M. et al. published their research in Journal of Organic Chemistry in 2021 |CAS: 578-58-5

The Article related to aralkyl ketone preparation, alkylarene aldehyde dehydrogenative cross coupling photoredox iridium complex catalyst, General Organic Chemistry: Synthetic Methods and other aspects.HPLC of Formula: 578-58-5

On October 1, 2021, Griffiths, Oliver M.; Esteves, Henrique A.; Chen, Yiding; Sowa, Karin; May, Oliver S.; Morse, Peter; Blakemore, David C.; Ley, Steven V. published an article.HPLC of Formula: 578-58-5 The title of the article was Photoredox-Catalyzed Dehydrogenative Csp3-Csp2 Cross-Coupling of Alkylarenes to Aldehydes in Flow. And the article contained the following:

Herein, the transfer of photoredox-catalyzed benzylic coupling of alkylarenes such as 4-methylanisole, tert-Bu 3-methyl-1H-indole-1-carboxylate, 2-methylfuran, etc. to aldehydes RCHO (R = pentyl, dec-9-en-1-yl, cyclopentyl, 1-[(tert-butoxy)carbonyl]piperidin-4-yl, etc.) to a flow chem. setting leading to improvements in terms of higher concentration, shorter residence times, better yields, ease of catalyst preparation, and enhanced substrate scope have been reported. Its applicability has been demonstrated by a multi-gram-scale reaction using high-power light-emitting diodes (LEDs), late-stage functionalization of selected active pharmaceutical ingredients (APIs), e.g., I, and also a photocatalyst recycling method. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).HPLC of Formula: 578-58-5

The Article related to aralkyl ketone preparation, alkylarene aldehyde dehydrogenative cross coupling photoredox iridium complex catalyst, General Organic Chemistry: Synthetic Methods and other aspects.HPLC of Formula: 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem