2-Azidoethane-1-sulfonylfluoride (ASF): A Versatile Bis-clickable Reagent for SuFEx and CuAAC Click Reactions was written by Zhang, Xu;Moku, Balakrishna;Leng, Jing;Rakesh, K. P.;Qin, Hua-Li. And the article was included in European Journal of Organic Chemistry in 2019.Category: ethers-buliding-blocks The following contents are mentioned in the article:
A new reagent, 2-azidoethane-1-sulfonylfluoride (ASF) was synthesized from 2-chloroethane-1-sulfonyl fluoride in 50g-scale with 87% yield. This novel reagent possesses two selectively clickable functionalities to be used for both CuAAC and SuFEx click reactions. The application of this reagent ASF to the construction of a class of novel 1,2,3-triazole derived S(VI)-F analogs was achieved in a quick, efficient and atom-economical manner. Orthogonally clickable construction of a new class of dendrimers was also accomplished. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Category: ethers-buliding-blocks).
4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Category: ethers-buliding-blocks
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem