Poole, Colin F. published the artcileEvaluation of the solvation parameter model as a quantitative structure-retention relationship model for gas and liquid chromatography, Related Products of ethers-buliding-blocks, the publication is Journal of Chromatography A (2020), 461308, database is CAplus and MEDLINE.
The Wayne State University (WSU) exptl. descriptor database is utilized to bench mark the current capability of the solvation parameter model for use as a quant. structure-retention relationship tool for estimating retention in gas and reversed-phase liquid chromatog. The prediction error for the retention factors of varied compounds on six open-tubular columns for gas chromatog. (Rtx-5 SIL MS, DB-35 ms, RtxCLPesticides, HP-88, HP-INNOWAX and SLB-IL76) and three packed columns for reversed-phase liquid chromatog. (SunFire C18, XBridge Shield RP18, and XBridge Phenyl) is used to establish expectations related to current practices. Each column data set was divided into a training set for calibration and a test set for validation employing a roughly 1 to 2 split, such that each test set contained about 40 to 80 varied compounds The average absolute error for the prediction of retention factors by gas chromatog. varied from about 0.1 to 0.4 on the retention factor scale with the larger error typical of stationary phases ranked as the most polar (or cohesive). For reversed-phase liquid chromatog. the average error for the prediction of retention factors was 0.3 to 0.5 and generally larger than for gas chromatog. Statistical filters where utilized to identify a group of polycyclic aromatic compounds without hydrogen-bonding functional groups with a larger prediction error on the SunFire C18 column than for other compounds of smaller size, flexible structure or containing hydrogen-bonding functional groups. The heterogeneity of the retention mechanism is speculated to be the main contribution to the prediction error for both gas and liquid chromatog. using the solvation parameter model.
Journal of Chromatography A published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Related Products of ethers-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem