Morimoto, Koji published the artcileCyclic Hypervalent Iodine-Induced Oxidative Phenol and Aniline Couplings with Phenothiazines, Safety of 4-Hydroxy-3-tert-butylanisole, the main research area is phenothiazineyl phenol chemoselective preparation; phenol phenothiazine cross coupling cyclic hypervalent iodine induced; amine phenothiazinyl chemoselective preparation; phenothiazine aryl amine cross coupling cyclic hypervalent iodine induced.
In this study, cyclic hypervalent iodine-induced metal-free cross-dehydrogenative coupling of phenols/amines with phenothiazines to afford (10H-phenothiazinyl)phenols I [R = 4,5-dimethoxy-2-phenolyl, 6-Br-4-OMe-2-phenolyl, 4-naphthalenolyl, etc.; R1 = H, OMe, Cl, CF3; X = O,S] and (10H-phenothiazinyl)amines II [R2 = N,N-diethyl-4-aniline, N,N-dimethyl-4-aniline, N-ethyl-2-methyl-4-aniline, etc.; R3 = H, Me, Cl, etc.; Y = O,S] was reported. This method afforded selective amination products I and II under mild conditions and in moderate-to-high yields. Aniline amination proceeded efficiently at 20°C, a previously unreported phenomenon.
Organic Letters published new progress about Amination. 121-00-6 belongs to class ethers-buliding-blocks, name is 4-Hydroxy-3-tert-butylanisole, and the molecular formula is C11H16O2, Safety of 4-Hydroxy-3-tert-butylanisole.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem