An Efficient Polymer Supported Palladium Catalyst for ortho Selective C-H Olefination of Anilides was written by Saranya, Thachora Venu;Sruthi, Pambingal Rajan;Ayana, Nambokkil;Anas, Saithalavi. And the article was included in ChemistrySelect in 2021.Application In Synthesis of N-(3-Methoxyphenyl)pivalamide This article mentions the following:
The development of a novel heterogeneous polymer supported palladium catalyst for the oxidative C-H olefination of anilides was described. The catalyst was realized by immobilizing palladium acetate over ethylene diamine modifiedpolyacrylonitrile (PAN) and characterized by means of FTIR, XRD and XPS analyses which evidenced the complexation of Pd(OAc)2 with the chelating groups in the polymer. The resulting supported complex (en-PAN-Pd) was then explored as an efficient and reusable heterogeneous catalyst for ortho selective C-H activation of anilides on reaction with a number of alkyl acrylates. This reaction protocol served as a useful and greener method for the synthesis of o-alkenyl anilides under mild reaction conditions. The catalyst also exhibited good recyclability and reusability without losing much catalytic activity. In the experiment, the researchers used many compounds, for example, N-(3-Methoxyphenyl)pivalamide (cas: 56619-93-3Application In Synthesis of N-(3-Methoxyphenyl)pivalamide).
N-(3-Methoxyphenyl)pivalamide (cas: 56619-93-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Application In Synthesis of N-(3-Methoxyphenyl)pivalamide
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem