Metalloporphyrin receptors for histidine-containing peptides was written by Liu, Hui;Li, Zhan-Ting. And the article was included in Chinese Chemical Letters in 2014.COA of Formula: C10H21NO4 This article mentions the following:
Two new ditopic metalloporphyrin receptors constructed by combining alkyl-strapped-porphyrin with crown ether arms and zinc acetate have been prepared and characterized. 1H NMR and MS spectra confirmed the complexation of the metalloporphyrin with the peptide driven by coordination interaction and hydrogen bonding. UV/visible experiments revealed that the receptors exhibited high binding affinity to histidine-containing peptides. These receptors could differentiate short peptides of C-terminal histidine and N-terminal histidine and formed the most stable complexes with tripeptide. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3COA of Formula: C10H21NO4).
1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.COA of Formula: C10H21NO4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem