Change in the rate of pseudo[1]rotaxane formation by elongating the alkyl-chain-substituted diphenylethynylene linked to permethyl α-cyclodextrin was written by Ishino, Saqura;Masai, Hiroshi;Shimada, Sotaro;Terao, Jun. And the article was included in Tetrahedron Letters in 2020.Product Details of 111-77-3 This article mentions the following:
Herein, we report the kinetics of pseudo[1]rotaxane formation from permethyl α-cyclodextrin attached to a flexible-chain-substituted diphenylethynylene. When the chain is an alkyl group, the rate of formation shows different trends over three regions of chain length: deceleration (chain length = 1-3), acceleration (4-8), and re-deceleration (>12). This behavior is driven by a relative decrease in the ΔH of the transition. In the experiment, the researchers used many compounds, for example, 2-(2-Methoxyethoxy)ethanol (cas: 111-77-3Product Details of 111-77-3).
2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Product Details of 111-77-3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem