Singh, Pashupati Prasad et al. published their research in Medicinal Chemistry: An Indian Journal in 2006 | CAS: 1877-75-4

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Electric Literature of C9H10O4

Quantitative structure activity relationship of inhibitors of glycolic acid oxidase was written by Singh, Pashupati Prasad;Kumar, Pragnesh;Marfatia, K.;Singh, Rajesh Kumar. And the article was included in Medicinal Chemistry: An Indian Journal in 2006.Electric Literature of C9H10O4 This article mentions the following:

In order to avoid trial and error method in selecting a suitable drug, QSAR methods have provided a rational basis to the design of enzyme inhibitors. 90 Derivatives of enzyme inhibitors, whose inhibitory potencies in term of PI50 are reported, have been used as study material for QSAR study. These derivatives are divided into five groups: (1) substituted glycolic acids, (2) substituted oxyacetic acids, (3) substituted glyoxylic acids, (4) substituted-3-hydroxy-1H pyrrole-2,5-diones derivatives, (5) 4-heterocyclic substituted 3-hydroxy-1H-pyrrole-2,5-diones derivatives The QSAR study and MLR anal. have been collectively made, because the potency is reported in one unit and the target enzyme glycolic acid oxidase (GAO) is common to all. The study has been made with the help of seven descriptors in different combinations: (1) Heat of formation (ΔHf), (2) HOMO energy (3) LUMO energy, (4) Absolute hardness (η) (5) Mol. weight (MW), (6) Electronegativity (χ) (7) Total energy (TE). This is perhaps for the first time when inhibitory potency has been related with quantum mech. parameters, without any significance to structure of compounds The values of descriptors have been obtained with the help of PC MODEL software using the semiempirical PM3 Hamiltonian. 32 Multi linear regression models using different combinations of descriptors have been developed using the project leader program associated with CAChe software. The predicted activity is close to the observed activity and the correlation coefficient is above 0.80. The best QSAR models are obtained by MLR anal. using the combinations, (i) heat of formation, mol. weight and electronegativity, (ii) mol. wight, total energy and electronegativity. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Electric Literature of C9H10O4).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Electric Literature of C9H10O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem