Synthesis of 2-aryloxyacetylamido-5-aryloxymethyl-1,3,4-thiadiazoles under solid-liquid phase transfer catalysis was written by Wang, Xicun;Li, Zheng;Ji, Dong;Da, Yuxia. And the article was included in Synthetic Communications in 2002.Application of 1877-75-4 This article mentions the following:
2-Aryloxyacetylamido-5-aryloxymethyl-1,3,4-thiadiazoles were synthesized by the reaction of aryloxyacetic acids with phenylsulfonyl chloride and 2-amino-5-aryloxymethyl-1,3,4-thiadiazoles under solid-liquid phase transfer catalysis. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Application of 1877-75-4).
2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Application of 1877-75-4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem