Selective monotetrahydropyranylation of symmetrical diols using P2O5/SiO2 under solvent-free conditions and their depyranylation was written by Eshghi, Hossein;Rahimizadeh, Mohammad;Saberi, Sattar. And the article was included in Chinese Chemical Letters in 2008.SDS of cas: 60221-37-6 This article mentions the following:
Selective protection of one of the hydroxyl group in 1,n-sym. diols is achieved by P2O5/SiO2-catalyzed reaction of the diol with dihydropyran under solvent-free conditions at room temperature This selective protection is simple and it occurred under economically cheap conditions in high yield. The deprotected diol is simply obtained by refluxing of this compound in methanol using the same catalyst without any byproduct formation or addnl. purifications. In the experiment, the researchers used many compounds, for example, 2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol (cas: 60221-37-6SDS of cas: 60221-37-6).
2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol (cas: 60221-37-6) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.SDS of cas: 60221-37-6
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem