Naturally occurring compounds related to phenalenone. Part 9. Synthesis of 8,9-dihydro-1,2,3,6-tetrahydroxy-4,8,8,9-tetramethylphenaleno[1,2-b]furan-7-one and 8,9-dihydro-1,4,5,6-tetrahydroxy-3,8,8,9-tetramethylphenaleno[1,2-b]furan-7-one was written by Halton, David D.;Morrison, George A.. And the article was included in Journal of Chemical Research, Synopses in 1979.Category: ethers-buliding-blocks This article mentions the following:
The title furanones (I; R = H, R1 = Me, R2 = R3 = OH; R = R1 = OH, R2 = Me, R3 = H, resp.) were prepared in 9 steps from 3,4,5-(MeO)3C6H2CH2CHO (II), for which an improved synthesis was developed. The key intermediate in the syntheses was the naphthalene III, obtained in 9.4% overall yield. In the experiment, the researchers used many compounds, for example, 3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8Category: ethers-buliding-blocks).
3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Category: ethers-buliding-blocks
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem