A New Route to E-Stilbenes through the Transition-Metal-Free KOtBu/DMF-Promoted Direct Coupling of Alcohols with Phenyl Acetonitriles was written by Liu, Xiaoping;Sotiropoulos, Jean-Marc;Taillefer, Marc. And the article was included in European Journal of Organic Chemistry in 2022.Related Products of 105-13-5 This article mentions the following:
An alternative route to synthesize alkenes, based only on the KOtBu/DMF promoted activation and direct coupling of alcs. with Ph acetonitriles, was reported. A variation allowing, through a Csp3-Csp3 bond formation, the selective synthesis of N-Heteroarenes was also described. A mechanism for the olefination pathway proceeding via an original activation of alcs. under alkyl formates was provided. In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5Related Products of 105-13-5).
(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Related Products of 105-13-5
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem