Blue-light Induced Iron-Catalyzed 浼?Alkylation of Ketones was written by Abdallah, Marie-Samira;Joly, Nicolas;Gaillard, Sylvain;Poater, Albert;Renaud, Jean-Luc. And the article was included in Organic Letters in 2022.Application In Synthesis of (4-Methoxyphenyl)methanol This article mentions the following:
A visible-light induced iron-catalyzed 浼?alkylation of ketones was reported. The photocatalytic system was based on the single diaminocyclopentadienone iron tricarbonyl complex. Two catalytic intermediates of this complex were able to harvest light allowing the synthesis of substituted aromatic and aliphatic ketones such as RC(O)CH2CH2R1 [R = t-Bu, 4-MeC6H4, 2-furyl, etc.; R1 = Ph, 2-thienyl, 4-BrC6H4, etc.] at room temperature using the borrowing hydrogen strategy in the presence of various substituted primary alcs. as alkylating reagents. Preliminary mechanistic studies unveiled the role of light for both the dehydrogenation and reduction step. In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5Application In Synthesis of (4-Methoxyphenyl)methanol).
(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Application In Synthesis of (4-Methoxyphenyl)methanol
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem