Chen, Chen et al. published their research in Bioorganic & Medicinal Chemistry in 2022 | CAS: 1877-75-4

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.HPLC of Formula: 1877-75-4

Design, synthesis, and antitumor activity evaluation of novel acyl sulfonamide spirodienones was written by Chen, Chen;Luo, Yang;Yin, Honglu;Zhong, Qiu;Zheng, Shilong;Liu, Rui;Zhao, Chong;Wang, Guangdi;He, Ling. And the article was included in Bioorganic & Medicinal Chemistry in 2022.HPLC of Formula: 1877-75-4 This article mentions the following:

Based on the promising results of benzenesulfonamide spirodienones as antineoplastic agents, a series of novel acyl sulfonamide spirodienones I [R = Me, C6H5, 4-MeC6H4, etc.; R1 = H, Me] were designed and synthesized for antineoplastic evaluation. Of these, compound I [R = 4-MeC6H4, R1 = H] exhibited remarkable in-vitro antiproliferative activity by arresting the cell cycle and inducing apoptosis of MDA-MB-231 cells. Acute toxicity study demonstrated that compound I [R = 4-MeC6H4, R1 = H] at 100 mg/kg dose caused no obvious toxicity to the major organs of mice. Moreover, compound I [R = 4-MeC6H4, R1 = H] suppressed the growth of murine 4T1 tumor in-vivo. Preliminary enzyme assay showed that I [R = 4-MeC6H4, R1 = H] was a potential MMP2 inhibitor for cancer therapy. In all, these results indicated that compound I [R = 4-MeC6H4, R1 = H] may be a lead compound for the development of anticancer agents. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4HPLC of Formula: 1877-75-4).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.HPLC of Formula: 1877-75-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem