Linear polystyrene-stabilized Pt nanoparticles catalyzed indole synthesis in water via aerobic alcohol oxidation was written by Ohtaka, Atsushi;Kozono, Mao;Takahashi, Kazuhiro;Hamasaka, Go;Uozumi, Yasuhiro;Shinagawa, Tsutomu;Shimomura, Osamu;Nomura, Ryoki. And the article was included in Chemistry Letters in 2016.Synthetic Route of C8H9NO3 This article mentions the following:
The one-pot synthesis of indoles in water by aerobic alc. oxidation and subsequent cyclization was achieved using linear polystyrene-stabilized Pt nanoparticles as a catalyst. The catalyst can be reused although a slight increase in particle size was observed by TEM of the recovered catalyst. In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitroanisole (cas: 5367-32-8Synthetic Route of C8H9NO3).
3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Synthetic Route of C8H9NO3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem