Shibasaki, Kaho; Togo, Hideo published an article in 2020, the title of the article was Facile preparation of 5-alkyl-1-aryltetrazoles with arenes, acyl chlorides, hydroxylamine, and diphenylphosphoryl azide.Synthetic Route of 578-58-5 And the article contains the following content:
Successive treatment of arenes with acyl chlorides and AlCl3, the addition of water and removal of solvent, the reaction with NH2OH·HCl and K2CO3, and the reaction with diphenylphosphoryl azide and DBU under warming conditions gave the corresponding 5-alkyl-1-aryltetrazoles efficiently in good to moderate yields. The present method is one-pot transformation of arenes into 5-alkyl-1-aryltetrazoles I (R = Me, iPr, Ph, etc.; R1 = 4-tBuC6H4, 4-MeOC6H4, 4-ClC6H4, etc.) using the Friedel-Crafts acylation and the Beckmann rearrangement under transition-metal-free conditions. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Synthetic Route of 578-58-5
The Article related to alkyl aryltetrazole preparation, arene acyl chloride friedel crafts acylation beckmann rearrangement, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Synthetic Route of 578-58-5
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem