Facile Hydrogenative Deprotection of N-Benzyl Groups Using a Mixed Catalyst of Palladium and Niobic Acid-on-Carbon was written by Yamamoto, Yuta;Shimizu, Eisho;Ban, Kazuho;Wada, Yoshiyuki;Mizusaki, Tomoteru;Yoshimura, Masatoshi;Takagi, Yukio;Sawama, Yoshinari;Sajiki, Hironao. And the article was included in ACS Omega in 2020.Electric Literature of C13H12O2 The following contents are mentioned in the article:
Nb2O5/C was prepared from activated carbon, H2O, and NbCl5; in the presence of a combination of Nb2O5/C and Pd/C, benzylamines, benzyl carbamates, and benzyl ethers underwent hydrogenolysis in MeOH to yield amines and alcs. The combination of Nb2O5/C and Pd/C was used five times for the debenzylation of N-benzyldioctylamine to give product in 82->97% yield with a decrease in yield in the fourth reaction. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Electric Literature of C13H12O2).
4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Electric Literature of C13H12O2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem