Environmentally friendly method for the iodination of moderately active arenes was written by Sathiyapriya, R.. And the article was included in Asian Journal of Chemistry in 2011.Recommanded Product: 75581-11-2 This article mentions the following:
An effective and environmentally friendly method for the iodination of various moderately active methoxy arenes, phenols and anilines using hydrogen peroxide and acidified sodium periodate in aqueous ethanol medium is reported. The extent of iodination is easily controlled by stoichiometry and excellent yields of mono iodinated products are obtained. In the experiment, the researchers used many compounds, for example, 4-Iodo-1-methoxy-2-methylbenzene (cas: 75581-11-2Recommanded Product: 75581-11-2).
4-Iodo-1-methoxy-2-methylbenzene (cas: 75581-11-2) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Recommanded Product: 75581-11-2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem