Rapid heteroatom transfer to arylmetals utilizing multifunctional reagent scaffolds was written by Gao, Hongyin;Zhou, Zhe;Kwon, Doo-Hyun;Coombs, James;Jones, Steven;Behnke, Nicole Erin;Ess, Daniel H.;Kurti, Laszlo. And the article was included in Nature Chemistry in 2017.Related Products of 104197-14-0 This article mentions the following:
Arylmetal reagents generated in situ from aryl bromides, aryl iodides, or arenes underwent chemoselective amination or hydroxylation reactions with an N-H oxaziridine and an N-benzyl oxaziridine derived from (-)-fenchone and racemic camphor, resp., to yield primary arylamines (as their free bases) and phenols, resp. The method does not use transition metal catalysts or added ligands or catalysts and does not require excess amounts of oxaziridine or nitrogen protecting groups. The structures of transition states leading to amination, hydroxylation, and proton transfer reactions were determined by DFT calculations to understand the chemoselectivity of N-H and N-protected aziridine reactions with 2-naphthylmagnesium bromide. In the experiment, the researchers used many compounds, for example, 4-Bromo-2,6-difluoroanisole (cas: 104197-14-0Related Products of 104197-14-0).
4-Bromo-2,6-difluoroanisole (cas: 104197-14-0) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Related Products of 104197-14-0
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem