A new method for the construction of indole nucleus was written by Iwao, Masatomo. And the article was included in Heterocycles in 1994.Recommanded Product: N-(3-Methoxyphenyl)pivalamide This article mentions the following:
Directed lithiation of N-tert-butoxycarbonylanilines I (X = H, Y = H, F, MeO; X = Me, CF3, MeO, Cl, F, Y = H) and subsequent reaction with 1-tert-butyldimethylsilyl-1-phenylsulfinylethene gave the conjugate addition products which, without isolation, were cyclized to 1-tert-butoxycarbonyl-2-(phenylthio)indolines II under thermal sila-Pummerer reaction conditions. In the experiment, the researchers used many compounds, for example, N-(3-Methoxyphenyl)pivalamide (cas: 56619-93-3Recommanded Product: N-(3-Methoxyphenyl)pivalamide).
N-(3-Methoxyphenyl)pivalamide (cas: 56619-93-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Recommanded Product: N-(3-Methoxyphenyl)pivalamide
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem