《Potentiometric screen-printed sensor for determination of oxybutynin hydrochloride》 was written by El-Attar, Rehab O.; Hendawy, Hassan A. M.; Khaled, Elmorsy. Application of 33100-27-5 And the article was included in Journal of the Iranian Chemical Society in 2020. The article conveys some information:
Abstract: The present work describes the fabrication of disposable screen-printed oxybutynin hydrochloride (OXB) potentiometric sensors. The electrode matrix composition was investigated on the basis of the effect of the nature and concentration of sensing ionophores, anionic sites, plasticizers and nanomaterials. Incorporation of single-walled carbon nanotubes (SWCNTs) as transducer and (2, 3, 6-tri-O-methyl)-β-cyclodextrin as mol. recognition elements in the electrode matrix improved both the sensitivity and selectivity of the sensor towards oxybutynin hydrochloride. The fabricated sensors showed Nernstian slope of 57.5 ± 1.0 mV decade-1 in the concentration range from 10-6 to 10-2 mol L-1 OXB with detection limit of 8 x 10-7 mol L-1. Moreover, the presence of SWCNTs in the electrode matrix enhanced the potential reading stability, response time (< 4 s) and increased life time of the sensors (5 mo). The developed sensors were successfully applied for determination of OXB in pharmaceutical formulations and biol. fluids with agreeable average recoveries compared with the official methods. The experimental part of the paper was very detailed, including the reaction process of 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Application of 33100-27-5)
1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Application of 33100-27-5
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem