Introduction of a new synthetic route about 27191-09-9

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Methoxyaniline hydrochloride, other downstream synthetic routes, hurry up and to see.

Adding a certain compound to certain chemical reactions, such as: 27191-09-9, name is 3-Methoxyaniline hydrochloride, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 27191-09-9, Quality Control of 3-Methoxyaniline hydrochloride

[0329] To the HCl salt of 3-methoxy-phenylamine (4.6 g, 28.9 mmol) in IN HCl(30O mL) was added a solution of 2-nitro-malonaldehyde (2.7 g, 19.3 mmol) in 15O mL water. After 30 min, the precipitate was filtered and rinsed with 0.1 N HCl. Air-drying in a Bchner funnel for 18 h gave 3.36 g (78%) of a light yellow/green powder. LC/MS (m/z): 245.1 (MH+ +Na), Rt 2.21 minutes.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Methoxyaniline hydrochloride, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; NOVARTIS AG; WO2007/84786; (2007); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem