Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 19500-02-8, name is 3-Methoxy-2-methylaniline, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 19500-02-8
2-Methoxy-4-bromotoluene; Crude 2-methoxy-6-amino-toluene (max. 120 mmol) was suspended in HBr (48percent, 48 ml) and water (120 ml) and cooled to 0¡ãC in an ice bath. Sodium nitrite (9.2 g) in water (24 ml) was added dropwise to the cold mixture, which turned yellow then brown. After 10 min, excess nitrite was destroyed by addition of urea (0.08 g) and the mixture was rapidly filtered into cold (0¡ãC) acetone (480 ml) to give a bright yellow solution. CuBr (99.999percent, 18.89,131 mmol) was then added portionwise and the resulting mixture stirred at 0¡ãC for 3h. Gas evolution was observed. The mixture was allowed to warm to ambient temperature, and then concentrated in vacuo. Dichloromethane was then added and the mixture washed with sat. aq. sodium bicarbonate solution. The organic layer was separated, dried over magnesium sulphate and concentrated in vacuo to give the product (23.1 g, 96percent) as a red oil. No.H (CDCl3; 250MHz) 7.18-6.77 (3H, m, aromatics), 3.83 (3H, s, OCH3), 2.32 (3H, s, CH3).
According to the analysis of related databases, 19500-02-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ARAKIS LTD.; WO2005/103019; (2005); A1;,
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