Synthetic Route of 16728-64-6, A common heterocyclic compound, 16728-64-6, name is 3-(Benzyloxy)propan-1-amine, molecular formula is C10H15NO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
(c) In an analogous manner to that described in Example 133 (b), from 3-benzyloxy-propylamine and tert-butyl (3RS,4RS)-4-(2-methylsulphonyl-pyrimidin-5-yl)-3-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylate [Example 129 (c)] there was obtained tert-butyl (3RS,4RS)-4-[2-(3-benzyloxy-propylamino)-pyrimidin-5-yl]-3-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylate in the form of a brownish gum; MS: 583 (M+H)+.
The synthetic route of 16728-64-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Hoffmann-La Roche Inc.; US6051712; (2000); A;,
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