Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 92248-06-1, name is Bis(3-methoxyphenyl)amine, A new synthetic method of this compound is introduced below., category: ethers-buliding-blocks
(3) The third step: under argon protection, add to the double-mouth bottle4,4 ‘, 4 “, 4” -tetrabromostatrene,3,3’-dimethoxydianiline, palladium acetate, sodium tert-butoxide and tri-tert-butylphosphine, adding 5 mL of toluene, stirring and placing at 130 C., reacting for 12 hours, stopping the reaction, adding saturated chlorinated The ammonium solution was extracted three times with dichloromethane and the organic layer was dried over anhydrous MgSO4. The crude product was subjected to silica gel column chromatography (petroleum ether: dichloromethane = 2: 3, v / v)A yellow solid was obtained,Recrystallization from tetrahydrofuran / petroleum ether. The product TPE-OMe-mm, the product of the formula as shown in formula (VI):
The synthetic route of 92248-06-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Sun Yat-sen University; Shao Guang; Kuang Daibin; He Yanjian; Chen Jian; (17 pag.)CN105037179; (2017); B;,
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