Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 54149-17-6, name is 1-Bromo-2-(2-methoxyethoxy)ethane, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 54149-17-6
To a vial containing ethyl 1H-indazoie-3-carboxyiate (150 mg, 0.789 inmol) in C1-I3CN (3 mL), were added I -bromo-2-(2-methoxyethoxy)etharie (217 mg, 1.183 mniol) and Cs?C03 (385 mg, 1.183 mrnol). The vial was sealed and the mixture was stirred at 80C overnight. Afterwards, water was added, extracted with EtOAc, washed organic layer with 10% LiCI, brine, concentrated and the residue was purified by normal phase chromatography with the second peak to elute off column being the desired product (105mg, 40.5%). MS (ESI) m/?: 293.2 (M±HY?. ?H NMR (400MHz, CDCI3) 5 8.20 (dt, J::r8.2,1.0 Hz, IH), 7.63- 7.57(m, 1H), 7.42 (ddd, J=8.4, 7.0, 1.1 Hz, IH), 7.30 (ddd, J=8.1,7.0, 0.9 Hz, 1H), 4.67 (t, J=5.6 Hz, 2H), 4.53 (q, J:::73 Hz, 21-1), 3.97 (t, J:::57 Hz. 21-1),3.56 – 3.48 (rn, 2H). 343 – 337 (m, 2H), 3.28 (s, 31:1), 1.48 (t, J:::7.2 Hz,3H).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 54149-17-6.